Radiation assumed during one's lifetime or in a short period of time may cause or triggerDNA mutations that lead to a variety of skin disorders up to and including Melanoma (indeed a disorder)
Certain chemicals in medication, "food", household, or environment may cause or triggerDNA mutations that lead to anything from respiratory problems (eg Asthma) to a variety of cancers (all of which are disorders as well).
Yet none of these genetic disorders can be passed on to offspring, becauseacquired DNA mutations are not heritable (as per current scientific knowledge).
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