Tumor (neoplasm) describes the condition of abnormal tissue growth because the respective cells divide more than healthy cells would or because they do not die when healthy cells would.
This is caused by the insufficient presence of PML molecules (and likely others) that in healthy cells are believed to regulate senescence (biological aging) and ultimately to enforce apoptosis (programmed cell death).
Malignant tumors differ from benign tumors in that they invade surrounding tissue or even metastasize (spread) to other parts of the body. In both cases they harm or destroy healthy cells.
Acute shock may have been caused by:
- any vaccination, because a vaccine consists of many alien substances that are injected directly into the bloodstream which shocks within seconds all body systems: Something that never happens in nature! Not even when a deadly virus enters the organism through mouth or nose.
- radiation, because an overdose of radiation shocks within seconds all body systems! This is not the radiation say from an x-ray though, these are well below shock levels.
- a chemical substance (in medication, "food", household, or environment), because at the "right" amount some substances that reach the bloodstream do indeed shock the entire organism: eg plastics, rubbers.
- rarely a pathogen, because some pathogens can literally overrun the cardiovascular system's defence mechanisms if they manage to enter the bloodstream directly, say through a lesion.
Chronic intoxication may have been caused by:
- industrial dog "food" or "treats"
- a chemical substance (in medication, "food", household, or environment) if it is perpetually or frequently
- inhaled, say room "refreshers", varnish, or smoke
- ingested, say scavenging yard care products like Roundup, or licking off floor cleaner detergent or wood paint
- absorbed through the skin, say carpet adhesives or cleaning or laundry detergents.
Some physicians however rightfully raise the question whether cancer can also be a defect, referring to the "only about 5% to 10% of all cancers [that] are thought to result directly from gene defects inherited from a parent".
What has been found are:
- a vast number of acquired DNA changes (variances) that are not heritable that many individuals share that have cancer. A great example is the TP53 gene abnormality that more than half of all human cancer cases share. No variance is shared by all, not even close!
- and a much smaller number of inherited DNA changes (mutations) in oncogenes and tumor suppressor genes that "run in families", those "5% to 10%". Again, up to more than half of those family members may have had cancer. These are the cases that label as "Family Cancer Syndromes" and make some physicians conclude that a few cancers are heritable.
If you now read our clear, precise, and disjunct defect definition in full, and if you fancy also inherited defect, you see that none of what has been found warrants the claim "a few cancers are heritable".
- A disorder is an acquired physiological dysfunction of an organ or body system that shows as over/under-production or over/under-utilization of a bodily substance...
- In the case of cancer there is an under-utilization (and maybe an under-production) of PML molecules (and likely others) that in healthy cells would prevent the uncontrolled tissue growth that describes cancer.
- Conversely, a defect is an inherited or acquired impairment of an organ, body structure, or body function other than a disorder.
All clear methodology aside, here are some interesting facts:
- Almost all cases of cancer (both in people and in dogs) show only later in life, and outside the biological transitions, after years if not decades of chronic intoxication that violated the Foundation of Health.
- The remaining few cases of cancer in newborns can be fully explained with having been acquired prenatal in the uterus or through the umbilical cord: Many disorders (and some defects and diseases too) are known to be transmitted to the unborn offspring if the mother is too sick (known or unknown) for the evolutionary protection mechanisms for offspring to fully take effect.
- Indeed in many cases it is known from medical records that before the baby was born the pregnant mother frequently violated the Foundation of Health: smoking, drinking, medication, and worse. This includes the massive nationwide Swedish Family-Cancer Database: 10 million records. Studies refer to people, no such studies on dogs.
- In addition, note that most newborns (both babies and puppies) already are subjected to injections and vaccinations that amount to an acute shock to all body systems of the young organism!
- It is obvious (common sense!) that the majority of these newborns then move on to develop health issues from those shocks to all body systems: skin problems following integumentary system disorders, intestinal problems following digestive system disorders, allergies and even cancer following immune system disorders, etc.
- A "family history of cancer" too does not suggest an inherited defect (click the link to see why). In fact, none of the factors they list here "make it more likely" that the particular cancer is inherited: all are easily explained with what you learned under defect and under inherited or acquired.
So really, we have every reason to consider cancer an acquired disorder, and no reason to accept the widely copied point of view that "genetics play an important role in the development of canine cancer" (and people cancer): they clearly don't.
How very different from the average owner who hasn't read this ultimate Dog Health Manual, isn't it?
Make sure you share this widely to reduce cancer risk for everyone interested.
Who Suffers Tumor/ Cancer
Like people, dogs are susceptible to a large variety of benign and malignant tumors in their skin, bones and organs. Because, like people (maybe more than people?) they are subjected to sustained cell intoxication with carcinogens in household products, yard products, medication, vaccines, food, etc.
It would be naive to assume one can persistently do harm to the organism's cells without health consequences, right? This aspect of health care is far underrated in media and medicine, that's why so few people care what they add to the organism on a daily basis.
Other than this generally applicable cause of sickness, purebred dogs with long lines of inbreeding (like what is happening to German Shepherds) are more likely to develop tumors because inbreeding reduces genetic variation and thus immunological responsiveness.
Where an unharmed immune system is able to identify and eliminate most nuances of cells that have gone awry, a weakened immune system will not be able to catch each of those. That's when those cells can uncontrollably proliferate to become a tumor.
This is why all over the world inbreeding among closely related people (incest) is punishable by law. Unfortunately this is not the case for dogs.
Finally, UNaltered dogs too are far more likely to develop cancer than those that have been safely spayed or neutered at a young age (6 months of age the latest).
Contrary to popular belief, the reason likely is more behavior-related than related to the impact that altering has on the endocrine system:
- Altered dogs do not "roam around", and so they have much less of a chance to get in contact with carcinogenic agents, whether pathogens transmitted by sick animals or their residues (excrement, dander, hair, saliva, etc) or whether chemical substances in the environment (landfill, garbage dump, pesticides, etc).
- Owners that alter their dog early or that acquire an altered dog tend to be more informed, considerate, and responsible in life in general, for example:
- regular health checks by a quality vet
- critical evaluation of the long-term benefit and risks of prescriptions and treatments
- avoiding environmental intoxication with chemicals etc
- feeding a REAL food natural diet
- administering remedies to safeguard the dog from worms, mosquitoes, ticks, fleas, mites, etc
- avoiding unnecessary vaccinations and all "boosters"!
Obviously, points 1 and 2 do not apply to each individual dog and owner, yet overall ie statistically these two points have the most significant ramifications for the likelihood of an individual dog to develop cancer.
The subsequent warning signs cover all types of cancer, but be aware that different types of cancer tend to have their characteristic symptoms. Overall, the most common cancer symptoms are:
- skin spots with unusual coloring, either suddenly appearing and persisting or continually growing
- sores or lesions that do not heal
- sudden weight loss without obvious reason
- loss of appetite without obvious reason
- unusual and unexplained bleeding
- unusual swelling anywhere on the body *
- repeatedly blood in vomit or urine or stool *
- unusual discharge from any body opening, incl. ears, eyes, nose *
- offensive odor from mouth or skin *
- difficulty when eating or swallowing *
- persistent hesitation to exercise (lethargy) or loss of stamina *
- persistent lameness or stiffness *
- difficulty breathing *
- difficulty urinating or defecating *
- pain when breathing or urinating or defecating *
- unexplained recurrent vomiting *
- unexplained recurrent diarrhea *
* These are specifically the symptoms of the types of cancer most common in German Shepherds.
These most common types of cancer in German Shepherds are:
- gastrointestinal tumors: foremost in the stomach, colon, pancreas, and esophagus
- osteosarcoma or chondrosarcoma: cancer of bones or cartilage
- lymphosarcoma or lymphoma: cancer of the immune system itself (lymphocytes)
- mast cell tumors: mast cells too are integral to the immune system, they fight pathogens primarily in the skin, intestines, and respiratory tract.
As you may have noticed, even just the symptoms of the most common types of cancer in German Shepherds can likewise characterize many other ailments. Therefore do not outright conclude "it's cancer!" when you notice some of these symptoms.
On the other hand, some of these symptoms will naturally come together, one after another. Therefore do see a quality veterinarian when you notice several symptoms in parallel or in sequence that will typically show in parallel or in sequence when a tumor is present.
An example will make this clearer:
Say for the second time within a week you notice there is blood in your dog's vomit (thus not necessarily consecutively). While you're wondering "How comes that?", you remember that recently you found your dog has been very lethargic, possibly even lame or stiff.
So now you start to analyze in your mind:
- "very lethargic and again vomiting blood"
- "it isn't hot summer now, and the dog is not eating any different than usual, nor is the dog exercising more than usual"
- "Could the dog have intestinal worms?"
- "Unlikely, (s)he's had deworming done last month"
- "A virus maybe?"
- "Unlikely, the dog is seven years old, had plenty of chances to acquire natural immunity, suffered no serious illness, and had no antibiotics nor steroids treatment"
- "It can't be cancer, can it?!?"
- "Wait, what's the dog getting to eat?"
- "Kibble. - Damn! So I really should have given the dog real food!"
- "I now better make an appointment with a quality vet for a complete blood test."
Remember this is just an example. Symptoms, dog's lifestyle and dog's living environment, as well as medical, exercise, and diet history of the dog, and how much common sense training you have acquired from mygermanshepherd.org or elsewhere, all factors play a role.
In short, only several symptoms together and the absence of certain other symptoms suggest a tumor, and indeed any other ailment.
A quality veterinarian, ideally in an animal hospital, will then confirm the preliminary diagnosis, and whether the tumor is benign or malignant.
Yet, ending my example with the conclusion to do a complete blood test was on purpose. Because, the most reliable means to confirm a cancer diagnosis are:
- Lab tests: identifying the existence and measuring the level of characteristic substances in body fluids like blood, urine, or saliva that together indicate tumorous cells anywhere in the body - cheapest, and always feasible.
- Biopsy: analyzing a tissue sample (taken per needle, endoscope, or surgery) in the lab - costly, and not always feasible.
- Imaging procedures: visually confirming unusual tissue growth per Ultrasound, CT scan, MRI, Radionuclide scan, PET scan, or X-ray - costly, and not always feasible.
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